The principle of complementarity: the essence of the concept and the basic laws of genetics

Complementarity - this property is two structures correspond to each other in a special way.

principle of complementarity is used in various spheres of human activity.So, the essence of complementarity in the learning process to the exact characteristics of the formation and development of students in a subject structure of schooling.In the field of composers it is associated with the use of citations, but the principle is the chemistry of space corresponds to the structure of two different molecules, which may arise between hydrogen bonding and intermolecular interaction.

principle of complementarity in biology regards compliance biopolymer molecules and various fragments.It ensures the formation of a definite relation between them (e.g., hydrophobic or electrostatic interactions between the charged functional groups).

This complementary fragments and bind biopolymers are not covalent chemical bond and spatial matched to each other to form weak links, which together have more energy, which leads to the formation of sufficiently stable complexes of molecules.In this case, the catalytic activity of the compounds depends on their complementarity to the intermediate catalytic reactions.

I must say that there is also a notion of structural correspondence of the two compounds.For instance, when the intermolecular interaction of protein complementarity - is the ability of ligands to approach each other at a close distance, that provides a strong correlation therebetween.

principle of complementarity in the field of genetic regard to the process of replication (doubling) of DNA.Each chain of the structure can serve as a template that is used in the synthesis of complementary strands that the final stage produces replicas of the original deoxyribonucleic acid.Thus there is a clear correspondence between the nitrogenous bases adenine, when coupled with thymine and guanine - only with cytosine.

oligo-and polynucleotides of nitrogenous bases form a corresponding pair complexes - A-T (A-U in RNA) or GC in the interaction of two strands of nucleic acids.This principle of complementarity plays a key role in ensuring the fundamental process of storage and transfer of genetic information.For example, a doubling of DNA during cell division, the process of DNA transcription into RNA, which is held with protein synthesis and repair processes (recovery) of DNA damage after they are impossible without respect for this principle.

If any irregularities in the strict allocation of the important components of different molecules in the body having a pathology which is clinically manifested genetic diseases.They can be transmitted to descendants or to be incompatible with life.

In addition, the principle is based komplementaranosti important analysis - PCR (polymerase chain reaction).With the help of detectors detect specific genetic DNA or RNA of various infectious or viral diseases in humans, helping to prescribe medication according to the etiology of the lesion.